Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12253/475
Full metadata record
DC FieldValueLanguage
dc.contributor.authorDuarte, N-
dc.contributor.authorJárdánházy, A-
dc.contributor.authorRamalhete, Cátia-
dc.contributor.authorMolnar, J-
dc.contributor.authorFerreira, MJU-
dc.date.accessioned2012-03-06T12:00:19Z-
dc.date.available2012-03-06T12:00:19Z-
dc.date.issued2007-
dc.identifier.citationInternational Congress and 55th Annual Meeting of the Society for Medicinal Plant Researchpt_PT
dc.identifier.urihttp://hdl.handle.net/10884/475-
dc.description.abstractThe aim of this study was to search for new multidrug resistance reversal agents from Euphorbia species. In this way, three new jatophane diterpenes (1 – 3) isolated from E.tuckeyana (Fig. 1) and three new lathyrane esters (4 - 6) obtained through acylation reations of latilagascene B (Fig. 4), have been screened for their potential P-gp modulating properties on mouse resistance cancer cell lines. Furthermore, in the combination chemotherapy model, the interaction between the cytostatic epirubicine and the six diterpenes were also evaluated.-
dc.language.isoengpt_PT
dc.rightsopenAccessen
dc.subjectDiterpenespt_PT
dc.subjectEpirubicinept_PT
dc.subjectCancerpt_PT
dc.titleSynergistic effects between macrocyclic diterpenes and doxorubicin on resistant cancer cellspt_PT
dc.typeconferenceObjectpt_PT
Appears in Collections:A CS/CN - Comunicações a Conferências

Files in This Item:
File Description SizeFormat 
2007_Graz_Latiranos_MDR.pdf617.24 kBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.